Across TCGA patient cohorts, CENPW mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible CENPW-associated genes across cancer lineages are RN7SL545P, RNU6-1289P, and MIR548T. Each is linked with CENPW in more than 1 cancer types. Because this analysis shows association rather than direction, both CENPW-to-partner and partner-to-CENPW results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPW→partner) and Y-score (partner→CENPW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	RN7SL545P →	+0.524	+8.025	<.001	.007	3	1
LUSC	RNU6-1289P →	+0.369	+5.151	<.001	.007	3	1
LUSC	MIR548T →	+0.477	+4.984	<.001	.009	3	1
LUSC	CYCSP43 →	+0.206	+5.151	.004	.007	3	1
LUSC	SNRPGP7 →	+0.381	+5.474	<.001	.005	3	1
LUSC	LINC00613 →	+1.215	+5.211	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

CENPW survival (RNA) · tumor vs normal (RNA) · all CENPW data types