CENPT

Across TCGA pan-cancer cohorts, CENPT Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CENPT data layer compared with 22 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CENPT Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CENPT expression acts as an unfavorable survival marker.

HNSC, LGG, and BLCA are the cancer types where CENPT Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	II,III,IV	0.010	0.757	<.001	36	view →
LGG	DFS	Median	All	0.110	0.833	<.001	6	view →
BLCA	OS	Median	All	0.164	0.592	.017	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CENPT–HNSC (OS)

Open the HNSC breakdown →