CENPS

Across TCGA cell cohorts, CENPS RNA expression is significantly associated with the go_rna of many other GO terms, with 3,359 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CENPS-associated GO terms across cancer lineages are Spindle elongation, DNA replication, and DNA-templated DNA replication. Each is linked with CENPS in more than 16 cancer types. Because this analysis shows association rather than direction, both CENPS-to-partner and partner-to-CENPS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle elongation grouped by CENPS-low versus CENPS-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPS→partner) and Y-score (partner→CENPS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Spindle elongation →	+0.173	+0.762	.002	.001	3	17
OESOPHAGUS	DNA replication →	+0.141	+0.926	<.001	.001	3	17
OESOPHAGUS	DNA-templated DNA replication →	+0.143	+0.926	.001	.001	3	17
OESOPHAGUS	DNA replication checkpoint signaling →	+0.224	+0.796	<.001	.001	3	16
BONE	DNA strand elongation →	+0.117	+0.556	.003	.004	3	16
OESOPHAGUS	Regulation of mitotic sister chromatid separation →	+0.212	+0.805	<.001	.002	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,359 associations by consensus.

Spindle elongation by CENPS expression — PANCREAS

Explore this box plot interactively →