CENPS

Across TCGA cell cohorts, CENPS protein abundance is significantly associated with the go_rna of many other GO terms, with 633 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CENPS-associated GO terms across cancer lineages are Purine nucleobase biosynthetic process, Regulation of kinase activity, and Regulation of protein kinase activity. Each is linked with CENPS in more than 3 cancer types. Because this analysis shows association rather than direction, both CENPS-to-partner and partner-to-CENPS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine nucleobase biosynthetic process grouped by CENPS-low versus CENPS-high in LARGE_INTESTINE.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPS→partner) and Y-score (partner→CENPS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Purine nucleobase biosynthetic process →	+0.227	+1.458	.004	.003	3	3
BREAST	Regulation of kinase activity →	+0.051	+2.005	.004	.003	3	3
BREAST	Regulation of protein kinase activity →	+0.055	+1.878	.007	.006	2	4
OVARY	Meiotic cell cycle process involved in oocyte maturation →	-0.232	-1.364	.001	.006	3	3
OVARY	Leukocyte migration involved in inflammatory response →	-0.385	-1.714	<.001	.004	3	3
OVARY	Adiponectin-activated signaling pathway →	+0.150	+1.712	.003	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 633 associations by consensus.

Purine nucleobase biosynthetic process by CENPS expression — LARGE_INTESTINE

Explore this box plot interactively →