Across TCGA patient cohorts, CENPP mutation is significantly associated with the RNA expression of many other genes, with 1,049 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CENPP-associated genes across cancer lineages are MIR7845, MIR4692, and GML. Each is linked with CENPP in more than 1 cancer types. Because this analysis shows association rather than direction, both CENPP-to-partner and partner-to-CENPP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPP→partner) and Y-score (partner→CENPP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7845 →	+0.419	+1.838	<.001	.008	3	2
UCEC	MIR4692 →	+0.228	+2.868	<.001	.009	3	2
PRAD	GML →	+0.053	+5.000	.002	.009	3	1
PRAD	CICP6 →	+0.024	+5.053	<.001	.009	3	1
PRAD	GEMIN2P2 →	+0.059	+5.109	.001	.008	3	1
PRAD	BLOC1S2P1 →	+0.139	+5.352	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,049 associations by consensus.

Exploration

CENPP survival (RNA) · tumor vs normal (RNA) · all CENPP data types