CENPO

Across TCGA patient cohorts, CENPO RNA expression is significantly associated with the protein abundance of many other proteins, with 26,591 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPO-associated proteins across cancer lineages are RRM2, SMC2, and SMC4. Each is linked with CENPO in more than 9 cancer types. Because this analysis shows association rather than direction, both CENPO-to-partner and partner-to-CENPO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPO versus RRM2 in LUAD, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPO→partner) and Y-score (partner→CENPO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RRM2 →	+0.880	+0.821	<.001	<.001	3	10
GBM	SMC2 →	+0.761	+0.662	<.001	<.001	3	10
GBM	SMC4 →	+0.722	+0.670	<.001	<.001	3	10
LUAD	NCL_S67 →	+0.890	+0.696	<.001	<.001	3	10
LUAD	BAZ1B_S349 →	+1.469	+0.881	<.001	<.001	3	10
LUAD	CDC20_T70 →	+1.197	+0.794	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,591 associations by consensus.

CENPO vs RRM2 — LUAD

Explore this scatter interactively →