CENPNP1

Across TCGA pan-cancer cohorts, CENPNP1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated CENPNP1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CENPNP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CENPNP1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and STAD show a favorable association.

KIRC, BLCA, and KICH are the cancer types where CENPNP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.504	0.668	<.001	170	view →
BLCA	OS	Tertile	III,IV	0.587	0.318	.006	87	view →
KICH	DFS	Tertile	All	0.079	0.891	<.001	75	view →
LIHC	DFS	Tertile	All	0.344	0.562	<.001	42	view →
THYM	OS	Quartile	All	0.841	1.000	.002	38	view →
BRCA	DFS	Tertile	All	0.140	1.000	.001	36	view →
COAD	OS	Tertile	IV	0.266	0.587	.008	27	view →
ACC	DFS	Tertile	II,III,IV	0.242	0.724	.034	18	view →
READ	DFS	Tertile	All	0.605	0.866	.021	15	view →
THCA	DFS	Tertile	All	0.845	0.927	.029	15	view →
STAD	OS	Quartile	IV	0.702	0.267	.013	14	view →
LGG	OS	Tertile	All	0.267	0.479	.022	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

CENPNP1–KIRC (OS)

Open the KIRC breakdown →