CENPNP1

Across TCGA pan-cancer cohorts, CENPNP1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CENPNP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CENPNP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CENPNP1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

HNSC and THCA are the cancer types where CENPNP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CENPNP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.022	.003	6	view →
THCA	All	All	−0.021	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

CENPNP1–HNSC

Open the HNSC breakdown →