CENPN

Across TCGA patient cohorts, CENPN protein abundance is significantly associated with the RNA expression of many other genes, with 12,066 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPN-associated genes across cancer lineages are CCNB2, BIRC5, and CDCA3. Each is linked with CENPN in more than 4 cancer types. Because this analysis shows association rather than direction, both CENPN-to-partner and partner-to-CENPN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPN versus CCNB2 in BRCA, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPN→partner) and Y-score (partner→CENPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CCNB2 →	+1.027	+0.466	.001	.003	3	5
BRCA	BIRC5 →	+1.207	+0.563	<.001	<.001	3	5
BRCA	CDCA3 →	+0.936	+0.422	<.001	.001	3	4
UCEC	ZWINT →	+1.096	+0.355	.005	.005	3	4
UCEC	HJURP →	+1.070	+0.475	<.001	.002	3	4
HNSC	CKS2 →	+1.158	+0.289	.007	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,066 associations by consensus.

CENPN vs CCNB2 — BRCA

Explore this scatter interactively →