CENPN

Across TCGA patient cohorts, CENPN protein abundance is significantly associated with the protein abundance of many other proteins, with 16,782 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPN-associated proteins across cancer lineages are AURKB, CDCA8_S219, and TRIP13. Each is linked with CENPN in more than 4 cancer types. Because this analysis shows association rather than direction, both CENPN-to-partner and partner-to-CENPN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPN versus AURKB in UCEC, with a Pearson correlation of 0.39.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPN→partner) and Y-score (partner→CENPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AURKB →	+0.952	+0.671	<.001	.001	3	5
OV	CDCA8_S219 →	+2.292	+0.912	.001	<.001	3	5
BRCA	TRIP13 →	+0.770	+0.594	<.001	<.001	3	5
LSCC	RFC3 →	+0.336	+0.402	<.001	<.001	3	5
OV	STMN1_S38 →	+1.169	+1.048	.001	<.001	3	5
BRCA	WRN_S1133 →	+0.823	+0.599	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,782 associations by consensus.

CENPN vs AURKB — UCEC

Explore this scatter interactively →