CENPN

Across TCGA cell cohorts, CENPN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,502 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CENPN-associated GO terms across cancer lineages are Nuclear division, Interstrand cross-link repair, and Meiotic chromosome segregation. Each is linked with CENPN in more than 18 cancer types. Because this analysis shows association rather than direction, both CENPN-to-partner and partner-to-CENPN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear division grouped by CENPN-low versus CENPN-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPN→partner) and Y-score (partner→CENPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Nuclear division →	+0.089	+1.601	.002	.001	3	19
OESOPHAGUS	Interstrand cross-link repair →	+0.111	+1.614	<.001	<.001	3	19
LARGE_INTESTINE	Meiotic chromosome segregation →	+0.124	+0.997	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Kinetochore assembly →	+0.170	+1.599	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Kinetochore organization →	+0.171	+1.600	<.001	<.001	3	19
KIDNEY	Mitotic metaphase chromosome alignment →	+0.108	+1.270	<.001	.002	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,502 associations by consensus.

Nuclear division by CENPN expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →