CENPJ

Across TCGA patient cohorts, CENPJ mutation is significantly associated with the RNA expression of many other genes, with 5,786 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CENPJ-associated genes across cancer lineages are SNORD116-22, OIP5, and C1QBP. Each is linked with CENPJ in more than 2 cancer types. Because this analysis shows association rather than direction, both CENPJ-to-partner and partner-to-CENPJ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD116-22 grouped by CENPJ-low versus CENPJ-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPJ→partner) and Y-score (partner→CENPJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	SNORD116-22 →	+0.506	+5.479	<.001	.002	3	3
UCEC	OIP5 →	+0.948	+2.984	<.001	<.001	3	3
COAD	C1QBP →	+0.655	+3.335	.003	.005	3	3
UCEC	KIF20A →	+0.613	+1.776	<.001	<.001	3	3
UCEC	SYT7 →	-0.792	-1.584	<.001	<.001	3	3
UCEC	RN7SL248P →	+0.036	+2.400	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,786 associations by consensus.

SNORD116-22 by CENPJ expression — LIHC

Explore this box plot interactively →