CENPI

Across TCGA cell cohorts, CENPI RNA expression is significantly associated with the go_rna of many other GO terms, with 4,454 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CENPI-associated GO terms across cancer lineages are Microtubule cytoskeleton organization involved in mitosis, DNA strand elongation, and CENP-A containing chromatin assembly. Each is linked with CENPI in more than 19 cancer types. Because this analysis shows association rather than direction, both CENPI-to-partner and partner-to-CENPI results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule cytoskeleton organization involved in mitosis grouped by CENPI-low versus CENPI-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPI→partner) and Y-score (partner→CENPI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Microtubule cytoskeleton organization involved in mitosis →	+0.121	+1.324	<.001	<.001	3	20
OESOPHAGUS	DNA strand elongation →	+0.209	+1.547	<.001	<.001	3	20
OESOPHAGUS	CENP-A containing chromatin assembly →	+0.179	+1.063	<.001	<.001	3	20
SKIN	Positive regulation of cell cycle →	+0.072	+1.157	<.001	<.001	3	20
LUNG_NSCLC_LUSC	Spindle elongation →	+0.285	+1.744	.001	.002	3	20
OESOPHAGUS	Kinetochore assembly →	+0.176	+1.133	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,454 associations by consensus.

Microtubule cytoskeleton organization involved in mitosis by CENPI expression — OESOPHAGUS

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