CENPE

Across TCGA patient cohorts, CENPE protein abundance is significantly associated with the RNA expression of many other genes, with 5,160 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPE-associated genes across cancer lineages are PIF1, AQP9, and CLEC4D. Each is linked with CENPE in more than 3 cancer types. Because this analysis shows association rather than direction, both CENPE-to-partner and partner-to-CENPE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPE versus PIF1 in BRCA, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPE→partner) and Y-score (partner→CENPE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PIF1 →	+0.587	+0.495	.003	.002	3	4
BRCA	AQP9 →	+1.198	+0.667	.001	.001	3	3
HNSC	CLEC4D →	+0.670	+1.009	.006	.001	2	4
LUAD	KIF18B →	+0.773	+0.558	.001	.002	3	3
LSCC	C16orf89 →	-1.417	-0.410	<.001	<.001	3	3
BRCA	PRR11 →	+0.680	+0.556	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,160 associations by consensus.

CENPE vs PIF1 — BRCA

Explore this scatter interactively →