CENPA

Across TCGA patient cohorts, CENPA RNA expression is significantly associated with the protein abundance of many other proteins, with 27,648 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPA-associated proteins across cancer lineages are PRC1_T481, PRIM2, and PURA. Each is linked with CENPA in more than 9 cancer types. Because this analysis shows association rather than direction, both CENPA-to-partner and partner-to-CENPA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPA versus PRC1_T481 in LUAD, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPA→partner) and Y-score (partner→CENPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PRC1_T481 →	+1.517	+1.050	<.001	<.001	3	10
OV	PRIM2 →	+0.555	+1.497	<.001	<.001	3	10
BRCA	PURA →	-0.445	-1.181	<.001	<.001	3	10
LUAD	TOP2A_S1213 →	+0.787	+1.267	<.001	<.001	3	10
LUAD	TRIP13 →	+0.998	+1.358	<.001	<.001	3	10
OV	NUF2_S247 →	+1.373	+1.394	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 27,648 associations by consensus.

CENPA vs PRC1_T481 — LUAD

Explore this scatter interactively →