Across TCGA cell cohorts, CENATAC mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible CENATAC-associated genes across cancer lineages are POTEB, OR13C2, and RGS21. Each is linked with CENATAC in more than 1 cancer types. Because this analysis shows association rather than direction, both CENATAC-to-partner and partner-to-CENATAC results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENATAC→partner) and Y-score (partner→CENATAC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	POTEB →	+0.016	+5.000	<.001	.006	3	1
PANCREAS	OR13C2 →	+0.012	+5.000	<.001	.006	3	1
LARGE_INTESTINE	RGS21 →	+0.033	+5.415	<.001	.004	3	1
LARGE_INTESTINE	CD300H →	+0.045	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

CENATAC survival (RNA) · tumor vs normal (RNA) · all CENATAC data types