CEMIP

Across TCGA patient cohorts, CEMIP mutation is significantly associated with the total protein of many other genes, with 59 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEMIP-associated genes across cancer lineages are eEF2, ER-alpha_pS118, and A-Raf_pS299. Each is linked with CEMIP in more than 3 cancer types. Because this analysis shows association rather than direction, both CEMIP-to-partner and partner-to-CEMIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by CEMIP-low versus CEMIP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEMIP→partner) and Y-score (partner→CEMIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.218	+1.099	.025	.016	3	4
SKCM	ER-alpha_pS118 →	+0.115	+1.584	.003	.016	3	4
UCEC	A-Raf_pS299 →	-0.096	-1.459	.003	.011	3	3
UCEC	Caspase-7-cleavedD198 →	+0.532	+1.543	<.001	.004	3	3
STAD	TFRC →	+0.835	+3.000	.009	.036	2	3
UCEC	EGFR_pY1068 →	-0.162	-0.951	.017	.037	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

eEF2 by CEMIP expression — UCEC

Explore this box plot interactively →