CEMIP

Across TCGA pan-cancer cohorts, CEMIP RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CEMIP’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CEMIP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CEMIP is over-expressed in tumor.

COAD, LUAD, and STAD are the cancer types where CEMIP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CEMIP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	+4.984	<.001	12	view →
LUAD	Male	III,IV	+3.580	<.001	9	view →
STAD	Male	II,III,IV	+3.072	<.001	9	view →
BLCA	Male	All	+1.743	<.001	8	view →
HNSC	Male	All	+1.551	<.001	8	view →
LIHC	Male	All	+0.806	<.001	8	view →
READ	Male	All	+5.883	<.001	7	view →
BRCA	All	II,III,IV	+2.094	<.001	6	view →
LUSC	Male	II,III,IV	+1.571	<.001	6	view →
CHOL	All	All	+2.282	<.001	5	view →
PAAD	All	All	+2.117	.040	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

CEMIP–COAD

Open the COAD breakdown →