CEMIP

Across TCGA cell cohorts, CEMIP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,492 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CEMIP-associated GO terms across cancer lineages are Regulation of protein kinase C activity, Positive regulation of protein kinase C activity, and Regulation of gastrulation. Each is linked with CEMIP in more than 10 cancer types. Because this analysis shows association rather than direction, both CEMIP-to-partner and partner-to-CEMIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein kinase C activity grouped by CEMIP-low versus CEMIP-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CEMIP→partner) and Y-score (partner→CEMIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of protein kinase C activity →	+1.036	+2.376	<.001	.007	3	11
LUNG_NSCLC_LUSC	Positive regulation of protein kinase C activity →	+1.036	+2.376	<.001	.007	3	11
OVARY	Regulation of gastrulation →	-0.122	-0.954	<.001	.001	3	11
BONE	Regulation of epithelial to mesenchymal transition →	+0.116	+2.311	<.001	<.001	3	9
BONE	Positive regulation of epithelial to mesenchymal transition →	+0.122	+2.228	<.001	.001	3	9
LUNG_SCLC	Positive regulation of intracellular protein transport →	+0.060	+1.535	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,492 associations by consensus.

Regulation of protein kinase C activity by CEMIP expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →