CELSR1

Across TCGA patient cohorts, CELSR1 protein abundance is significantly associated with the protein abundance of many other proteins, with 24,377 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CELSR1-associated proteins across cancer lineages are CELSR1_S2960, CELSR1_S2867, and CELSR1_S2761. Each is linked with CELSR1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CELSR1-to-partner and partner-to-CELSR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CELSR1 versus CELSR1_S2960 in LSCC, with a Pearson correlation of 0.85.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CELSR1→partner) and Y-score (partner→CELSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CELSR1_S2960 →	+1.187	+0.624	<.001	<.001	3	9
OV	CELSR1_S2867 →	+1.789	+0.989	<.001	<.001	3	7
LSCC	CELSR1_S2761 →	+1.338	+0.635	<.001	<.001	3	7
HNSC	FNBP1 →	-0.514	-0.341	<.001	<.001	3	7
OV	ANKRD44 →	-0.644	-0.479	<.001	<.001	3	6
BRCA	CELSR1_T2759 →	+2.267	+1.089	.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,377 associations by consensus.

CELSR1 vs CELSR1_S2960 — LSCC

Explore this scatter interactively →