CELSR1

Across TCGA cell cohorts, CELSR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,965 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CELSR1-associated GO terms across cancer lineages are Cerebral cortex radial glia-guided migration, Telencephalon glial cell migration, and Positive regulation of Notch signaling pathway. Each is linked with CELSR1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CELSR1-to-partner and partner-to-CELSR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cerebral cortex radial glia-guided migration grouped by CELSR1-low versus CELSR1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CELSR1→partner) and Y-score (partner→CELSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Cerebral cortex radial glia-guided migration →	+0.195	+1.644	<.001	<.001	3	9
KIDNEY	Telencephalon glial cell migration →	+0.195	+1.644	<.001	<.001	3	9
STOMACH	Positive regulation of Notch signaling pathway →	+0.111	+1.532	<.001	.002	3	9
BLOOD_Myeloma	Dichotomous subdivision of an epithelial terminal unit →	+1.050	+1.940	.006	.007	2	10
UPPER_AERODIGESTIVE_TRACT	Protein destabilization →	+0.070	+0.806	.001	.005	3	8
LUNG_SCLC	Retrograde transport, endosome to Golgi →	+0.051	+1.739	.002	.006	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,965 associations by consensus.

Cerebral cortex radial glia-guided migration by CELSR1 expression — KIDNEY

Explore this box plot interactively →