CELF6

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CELF6 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CELF6-associated genes across cancer lineages are MAGEB4, SPACA5, and TAS1R2. Each is linked with CELF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both CELF6-to-partner and partner-to-CELF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by CELF6-low versus CELF6-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CELF6→partner) and Y-score (partner→CELF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINMAGEB4 →+0.010+5.022<.001.00231
SKINSPACA5 →+0.063+4.273.001.00631
SKINTAS1R2 →+0.012+5.217<.001<.00131
SKINOR13D1 →+0.033+4.930<.001.00131
SKINTEX49 →+0.036+4.415<.001.00731
LARGE_INTESTINEELOA3DP →+0.023+4.273.003.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

MAGEB4 by CELF6 expression — SKIN

Box plot of MAGEB4 in CELF6-low vs CELF6-high samples in SKIN.

Explore this box plot interactively →

Exploration