CELF5

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CELF5 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated CELF5 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher CELF5 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CELF5 expression acts as an unfavorable survival marker.

LIHC are the cancer types where CELF5 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCDFSMedianAll0.0460.553<.00112view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

CELF5–LIHC (DFS)

Kaplan–Meier survival curve for CELF5 mutant vs wild-type samples in LIHC.

Open the LIHC breakdown →

Exploration