CELF5

Across TCGA pan-cancer cohorts, CELF5 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CELF5’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where CELF5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CELF5 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

LUAD, KICH, and BRCA are the cancer types where CELF5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CELF5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	II,III,IV	+0.604	<.001	9	view →
KICH	Female	II,III,IV	+1.750	<.001	7	view →
BRCA	Female	II,III,IV	−0.510	<.001	6	view →
LUSC	Male	II,III,IV	+0.479	<.001	5	view →
COAD	Male	II,III,IV	+0.356	.013	5	view →
KIRP	All	All	+0.332	.006	5	view →
LIHC	All	All	+0.377	.001	4	view →
KIRC	All	All	+0.256	.008	4	view →
THCA	All	All	+0.211	.001	4	view →
PRAD	All	All	+0.374	<.001	2	view →
CHOL	All	All	+1.178	.008	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

CELF5–LUAD

Open the LUAD breakdown →