CELF5

Across TCGA patient cohorts, CELF5 mutation is significantly associated with the RNA expression of many other genes, with 440 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CELF5-associated genes across cancer lineages are TNPO3P1, RN7SL813P, and OR51I2. Each is linked with CELF5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CELF5-to-partner and partner-to-CELF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNPO3P1 grouped by CELF5-low versus CELF5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CELF5→partner) and Y-score (partner→CELF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TNPO3P1 →	+0.054	+3.186	.009	.002	3	2
CESC	RN7SL813P →	+0.218	+5.103	<.001	.008	3	2
CESC	OR51I2 →	+0.057	+5.812	<.001	.003	3	2
CESC	RN7SKP213 →	+0.192	+5.010	<.001	.009	3	2
CESC	RPL9P13 →	+0.117	+5.010	<.001	.009	3	2
CESC	RPL31P45 →	+0.093	+5.201	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 440 associations by consensus.

TNPO3P1 by CELF5 expression — UCEC

Explore this box plot interactively →