CELF5

Across TCGA cell cohorts, CELF5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,698 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CELF5-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Regulation of myoblast fusion, and Negative regulation of myoblast fusion. Each is linked with CELF5 in more than 12 cancer types. Because this analysis shows association rather than direction, both CELF5-to-partner and partner-to-CELF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by CELF5-low versus CELF5-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CELF5→partner) and Y-score (partner→CELF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.097	+0.209	<.001	.001	3	13
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.096	+0.171	<.001	.006	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.104	+0.114	<.001	.005	3	11
OVARY	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.150	+0.666	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.091	+0.209	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.129	+0.180	.003	.009	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,698 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by CELF5 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →