CELF4

Across TCGA pan-cancer cohorts, CELF4 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated CELF4 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher CELF4 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CELF4 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

OV, LUAD, and SARC are the cancer types where CELF4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.028	0.844	<.001	48	view →
LUAD	DFS	Median	All	0.201	0.818	<.001	26	view →
SARC	OS	Median	All	0.133	0.860	<.001	12	view →
UCEC	DFS	Median	All	0.960	0.826	.015	12	view →
LUSC	OS	Median	II,III,IV	0.268	0.620	.017	7	view →
KIRC	OS	Median	All	0.249	0.810	.011	6	view →
COAD	OS	Median	III,IV	0.208	0.791	.008	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

CELF4–OV (OS)

Open the OV breakdown →