CELF4

Across TCGA pan-cancer cohorts, CELF4 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of CELF4’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where CELF4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CELF4 is over-expressed in tumor, although a few such as COAD and READ show the opposite, repressed pattern.

THCA, COAD, and READ are the cancer types where CELF4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CELF4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	+1.875	<.001	11	view →
COAD	Male	All	−0.453	<.001	10	view →
READ	All	All	−0.628	<.001	3	view →
CHOL	All	All	+0.605	.004	3	view →
STAD	All	IV	−0.510	.007	3	view →
KIRP	All	All	+0.350	.013	2	view →
LUAD	All	All	+0.288	.026	2	view →
BRCA	All	All	+0.169	.024	2	view →
PRAD	All	All	−0.143	.041	2	view →
ESCA	All	All	−0.746	.009	1	view →
LUSC	Female	III,IV	−0.315	.003	1	view →
LIHC	Female	II,III,IV	+0.067	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

CELF4–THCA

Open the THCA breakdown →