CELF4

Across TCGA patient cohorts, CELF4 mutation is significantly associated with the RNA expression of many other genes, with 2,891 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CELF4-associated genes across cancer lineages are NCAPD3, TYMS, and LRRC57. Each is linked with CELF4 in more than 3 cancer types. Because this analysis shows association rather than direction, both CELF4-to-partner and partner-to-CELF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NCAPD3 grouped by CELF4-low versus CELF4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CELF4→partner) and Y-score (partner→CELF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NCAPD3 →	+0.577	+2.153	.002	.009	3	4
COAD	TYMS →	+0.715	+2.700	.001	.006	3	4
UCEC	LRRC57 →	+0.315	+1.467	.001	.007	3	3
UCEC	ZSCAN22 →	+0.258	+2.078	.002	<.001	3	3
SKCM	PRC1 →	+0.653	+3.632	.002	.001	3	3
UCEC	RNA5SP492 →	+0.178	+1.846	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,891 associations by consensus.

NCAPD3 by CELF4 expression — SKCM

Explore this box plot interactively →