CELF4

Across TCGA cell cohorts, CELF4 mutation is significantly associated with the RNA expression of many other genes, with 207 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CELF4-associated genes across cancer lineages are OR8B3, OR11H2, and PROP1. Each is linked with CELF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CELF4-to-partner and partner-to-CELF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8B3 grouped by CELF4-low versus CELF4-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CELF4→partner) and Y-score (partner→CELF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR8B3 →	+0.055	+4.371	<.001	.005	3	2
SKIN	OR11H2 →	+0.047	+4.977	<.001	.007	3	2
LARGE_INTESTINE	PROP1 →	+0.019	+2.317	<.001	.004	3	2
BLOOD_Leukemia	RNASE7 →	+0.037	+3.579	.004	.007	3	1
BLOOD_Leukemia	KRTAP4-3 →	+0.051	+4.247	<.001	.004	3	1
BLOOD_Leukemia	CENPVL3 →	+0.530	+3.359	.006	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 207 associations by consensus.

OR8B3 by CELF4 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →