CELF3

Across TCGA patient cohorts, CELF3 mutation is significantly associated with the RNA expression of many other genes, with 3,994 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CELF3-associated genes across cancer lineages are LPCAT2BP, RNA5SP413, and RNA5SP423. Each is linked with CELF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CELF3-to-partner and partner-to-CELF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LPCAT2BP grouped by CELF3-low versus CELF3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CELF3→partner) and Y-score (partner→CELF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LPCAT2BP →	+0.022	+3.766	.001	.005	3	2
LUSC	RNA5SP413 →	+0.737	+5.081	<.001	.004	3	2
LUSC	RNA5SP423 →	+0.639	+5.733	<.001	.001	3	2
LUSC	MIR4310 →	+0.543	+5.906	<.001	.001	3	2
UCEC	ATP6V1D →	+0.435	+2.378	<.001	<.001	3	2
UCEC	USP14 →	+0.459	+3.346	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,994 associations by consensus.

LPCAT2BP by CELF3 expression — SKCM

Explore this box plot interactively →