CELF2-DT

Across TCGA pan-cancer cohorts, CELF2-DT RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated CELF2-DT data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CELF2-DT RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CELF2-DT expression acts as an unfavorable survival marker, although some lineages such as BLCA and KICH show a favorable association.

KIRC, UCEC, and READ are the cancer types where CELF2-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.320	0.670	.003	96	view →
UCEC	OS	Tertile	All	0.871	0.934	.003	90	view →
READ	DFS	Tertile	All	0.269	0.819	.009	45	view →
LUAD	OS	Tertile	III,IV	0.289	0.696	.005	36	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	30	view →
THYM	DFS	Tertile	III,IV	0.211	0.820	.006	27	view →
BLCA	OS	Tertile	IV	1.000	0.254	.018	27	view →
COAD	DFS	Tertile	II,III,IV	0.135	0.492	.022	27	view →
THCA	DFS	Tertile	All	0.600	0.920	.022	18	view →
SARC	OS	Quartile	All	0.652	0.812	.011	11	view →
PCPG	DFS	Tertile	All	0.752	0.932	.012	9	view →
BRCA	DFS	Tertile	All	0.916	0.952	.037	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

CELF2-DT–KIRC (DFS)

Open the KIRC breakdown →