CELA2A

Across TCGA pan-cancer cohorts, CELA2A Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CELA2A data layer compared with 23 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher CELA2A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CELA2A expression acts as an unfavorable survival marker.

READ, KIRP, and PRAD are the cancer types where CELA2A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Median	II,III,IV	0.111	0.919	<.001	45	view →
KIRP	OS	Median	All	0.199	0.903	<.001	15	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
SKCM	DFS	Median	III,IV	0.153	0.653	.022	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CELA2A–READ (OS)

Open the READ breakdown →