CELA2A

Across TCGA pan-cancer cohorts, CELA2A RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of CELA2A’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where CELA2A RNA is repressed in tumor relative to normal tissue. In most cancer types CELA2A is over-expressed in tumor, although a few such as KICH and LUAD show the opposite, repressed pattern.

KICH, LUAD, and LIHC are the cancer types where CELA2A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CELA2A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−0.085	.002	6	view →
LUAD	Female	All	−0.071	.015	6	view →
LIHC	Female	II,III,IV	+0.058	.001	3	view →
BRCA	All	IV	+0.125	.037	2	view →
HNSC	Male	All	+0.047	.033	2	view →
CHOL	Male	All	+0.041	.011	2	view →
STAD	Male	IV	−0.155	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

CELA2A–KICH

Open the KICH breakdown →