CELA2A

Across TCGA cell cohorts, CELA2A mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CELA2A-associated genes across cancer lineages are CCT8L2, OR6C3, and OR52E4. Each is linked with CELA2A in more than 1 cancer types. Because this analysis shows association rather than direction, both CELA2A-to-partner and partner-to-CELA2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCT8L2 grouped by CELA2A-low versus CELA2A-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CELA2A→partner) and Y-score (partner→CELA2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CCT8L2 →	+0.086	+6.022	<.001	.001	3	1
SKIN	OR6C3 →	+0.022	+5.415	<.001	.004	3	1
BLOOD_Leukemia	OR52E4 →	+0.015	+5.201	<.001	.006	3	1
BLOOD_Leukemia	ZCCHC13 →	+0.030	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	GRXCR1 →	+0.023	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	OR11H2 →	+0.074	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

CCT8L2 by CELA2A expression — SKIN

Explore this box plot interactively →