CEL

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CEL protein abundance is significantly associated with the RNA expression of many other genes, with 4,141 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEL-associated genes across cancer lineages are PCYT1B, UBE2I, and RAI1. Each is linked with CEL in more than 1 cancer types. Because this analysis shows association rather than direction, both CEL-to-partner and partner-to-CEL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CEL versus PCYT1B in UCEC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEL→partner) and Y-score (partner→CEL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPCYT1B →+0.751+0.819.001<.00132
UCECUBE2I →-0.286-0.663.001.00632
UCECRAI1 →-0.567-0.879.002.00432
UCECSLC1A2 →+1.097+1.432<.001<.00132
UCECSLC35F2 →-0.922-0.908<.001.00232
LSCCC6orf62 →-0.471-1.299.006.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,141 associations by consensus.

CEL vs PCYT1B — UCEC

Per-sample scatter of CEL vs PCYT1B in UCEC (Pearson r = 0.34).

Explore this scatter interactively →

Exploration