CECR2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CECR2 mutation is significantly associated with the RNA expression of many other genes, with 3,768 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CECR2-associated genes across cancer lineages are MRTO4, SLAMF9, and RAET1K. Each is linked with CECR2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CECR2-to-partner and partner-to-CECR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRTO4 grouped by CECR2-low versus CECR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CECR2→partner) and Y-score (partner→CECR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMRTO4 →+0.283+2.673.001<.00134
COADSLAMF9 →+0.698+2.013<.001.00534
UCECRAET1K →+0.282+2.102<.001<.00134
UCECBMS1P20 →+0.281+1.818.003.00234
BRCAFAM223A →+0.023+3.215<.001.00633
UCECRPARP-AS1 →+0.347+1.505<.001.00333
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,768 associations by consensus.

MRTO4 by CECR2 expression — UCEC

Box plot of MRTO4 in CECR2-low vs CECR2-high samples in UCEC.

Explore this box plot interactively →

Exploration