CECR2

Across TCGA pan-cancer cohorts, CECR2 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated CECR2 data layer compared with 8 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher CECR2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CECR2 expression acts as an unfavorable survival marker, although some lineages such as UCS and LGG show a favorable association.

UCS, KIRC, and ACC are the cancer types where CECR2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	II,III,IV	0.635	0.264	.005	70	view →
KIRC	DFS	Quartile	II,III,IV	0.442	0.730	<.001	64	view →
ACC	DFS	Median	All	0.289	0.648	<.001	58	view →
SKCM	OS	Median	All	0.292	0.465	.004	40	view →
LGG	OS	Quartile	All	0.636	0.354	.001	21	view →
GBM	DFS	Quartile	All	0.373	0.210	.008	19	view →
UCEC	OS	Tertile	All	0.836	0.913	.010	16	view →
BRCA	DFS	Quartile	IV	0.346	0.916	.017	14	view →
THYM	OS	Tertile	II,III,IV	0.780	1.000	.024	13	view →
HNSC	OS	Median	II,III,IV	0.291	0.453	.007	13	view →
DLBC	DFS	Median	All	1.000	0.382	.013	12	view →
UVM	OS	Median	II,III,IV	0.823	0.596	.007	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

CECR2–UCS (OS)

Open the UCS breakdown →