CECR2

Across TCGA patient cohorts, CECR2 mutation is significantly associated with the total protein of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CECR2-associated genes across cancer lineages are PDCD4, PCNA, and STAT3_pY705. Each is linked with CECR2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CECR2-to-partner and partner-to-CECR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by CECR2-low versus CECR2-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CECR2→partner) and Y-score (partner→CECR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	PDCD4 →	-0.618	-3.000	.007	.036	3	4
UCEC	PCNA →	+0.179	+1.398	.003	.004	3	4
BRCA	STAT3_pY705 →	-0.453	-3.000	.003	.038	3	3
UCEC	eIF4E →	+0.154	+1.584	.010	.001	3	3
UCEC	p38-MAPK_pT180_Y182 →	-0.295	-1.209	.021	.012	3	3
UCEC	ATM →	-0.554	-2.000	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

PDCD4 by CECR2 expression — STAD

Explore this box plot interactively →