CECR2

Across TCGA cell cohorts, CECR2 mutation is significantly associated with the RNA expression of many other genes, with 852 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CECR2-associated genes across cancer lineages are ZNF324B, ZNF705A, and NPRL2. Each is linked with CECR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CECR2-to-partner and partner-to-CECR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF324B grouped by CECR2-low versus CECR2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CECR2→partner) and Y-score (partner→CECR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ZNF324B →	+0.528	+2.158	.001	.004	3	3
LUNG_SCLC	ZNF705A →	+0.053	+3.807	<.001	.006	3	2
LARGE_INTESTINE	NPRL2 →	+0.494	+3.404	<.001	<.001	3	2
SKIN	WRAP73 →	+0.498	+3.339	<.001	.001	3	2
SKIN	ZNF780B →	+0.543	+3.257	.006	.002	3	2
SKIN	KLRG1 →	+0.745	+2.459	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 852 associations by consensus.

ZNF324B by CECR2 expression — SKIN

Explore this box plot interactively →