CEBPZ

Across TCGA patient cohorts, CEBPZ mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEBPZ-associated genes across cancer lineages are GAPDH, MEK1, and Cyclin-B1. Each is linked with CEBPZ in more than 1 cancer types. Because this analysis shows association rather than direction, both CEBPZ-to-partner and partner-to-CEBPZ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by CEBPZ-low versus CEBPZ-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEBPZ→partner) and Y-score (partner→CEBPZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GAPDH →	+0.755	+2.815	.006	.036	3	2
UCEC	MEK1 →	+0.428	+2.807	.001	.002	3	2
UCEC	Cyclin-B1 →	+0.776	+2.807	<.001	<.001	3	2
UCEC	14-3-3_beta →	-0.088	-2.088	.015	.016	3	2
UCEC	eIF4E →	+0.194	+3.700	.010	.001	3	2
UCEC	A-Raf_pS299 →	-0.142	-2.584	<.001	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

GAPDH by CEBPZ expression — COAD

Explore this box plot interactively →