CEBPZ

Across TCGA pan-cancer cohorts, CEBPZ RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of CEBPZ’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CEBPZ RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CEBPZ is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

HNSC, THCA, and LIHC are the cancer types where CEBPZ tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CEBPZ RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	+0.876	<.001	11	view →
THCA	All	IV	−0.852	<.001	10	view →
LIHC	All	II,III,IV	+0.852	<.001	9	view →
KICH	Female	II,III,IV	−1.804	<.001	6	view →
CHOL	All	All	+1.568	<.001	5	view →
LUSC	Male	All	+0.630	<.001	5	view →
STAD	All	II,III,IV	+0.647	.001	4	view →
COAD	Male	All	+0.523	.001	4	view →
LUAD	All	All	+0.241	.002	3	view →
ESCA	Female	All	+1.176	.009	2	view →
UCEC	All	All	−0.607	.013	2	view →
KIRP	Male	All	−0.473	.004	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

CEBPZ–HNSC

Open the HNSC breakdown →