CEBPZ

Across TCGA cell cohorts, CEBPZ mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEBPZ-associated genes across cancer lineages are PLVAP, IL20, and OR4F4. Each is linked with CEBPZ in more than 1 cancer types. Because this analysis shows association rather than direction, both CEBPZ-to-partner and partner-to-CEBPZ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PLVAP grouped by CEBPZ-low versus CEBPZ-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEBPZ→partner) and Y-score (partner→CEBPZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PLVAP →	+0.175	+2.648	.004	.008	3	1
LARGE_INTESTINE	IL20 →	+0.161	+2.984	.001	.005	3	1
LARGE_INTESTINE	OR4F4 →	+0.015	+3.009	<.001	.001	3	1
LARGE_INTESTINE	PYDC2 →	+0.078	+3.415	<.001	.001	3	1
LUNG_SCLC	IL3 →	+0.055	+5.029	<.001	.006	3	1
LUNG_SCLC	PRAMEF10 →	+1.180	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

PLVAP by CEBPZ expression — LARGE_INTESTINE

Explore this box plot interactively →