CEBPG

Across TCGA patient cohorts, CEBPG mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEBPG-associated genes across cancer lineages are TFRC, MEK1, and EGFR_pY1068. Each is linked with CEBPG in more than 2 cancer types. Because this analysis shows association rather than direction, both CEBPG-to-partner and partner-to-CEBPG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by CEBPG-low versus CEBPG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEBPG→partner) and Y-score (partner→CEBPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.678	+3.700	<.001	.001	3	3
UCEC	MEK1 →	+0.395	+2.321	.003	.005	3	2
UCEC	EGFR_pY1068 →	-0.268	-2.247	.003	.001	3	2
UCEC	PDCD4 →	-0.490	-1.502	.004	.030	3	2
UCEC	TSC1 →	-0.161	-2.420	.010	.018	3	2
UCEC	C-Raf →	+0.163	+1.847	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

TFRC by CEBPG expression — UCEC

Explore this box plot interactively →