Across TCGA pan-cancer cohorts, CEBPG RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of CEBPG’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CEBPG RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CEBPG is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
KIRC, HNSC, and STAD are the cancer types where CEBPG tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CEBPG RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.