CEBPB

Across TCGA patient cohorts, CEBPB mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEBPB-associated genes across cancer lineages are MIR378E, OR6K6, and RNU6-1082P. Each is linked with CEBPB in more than 1 cancer types. Because this analysis shows association rather than direction, both CEBPB-to-partner and partner-to-CEBPB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR378E grouped by CEBPB-low versus CEBPB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEBPB→partner) and Y-score (partner→CEBPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR378E →	+1.250	+6.453	<.001	.001	3	1
UCEC	OR6K6 →	+0.239	+5.358	<.001	.006	3	1
UCEC	RNU6-1082P →	+0.826	+5.551	<.001	.004	3	1
UCEC	SNORD114-18 →	+1.268	+5.299	<.001	.006	3	1
UCEC	OR6K3 →	+0.195	+4.982	<.001	.009	3	1
UCEC	RNU6-1292P →	+1.203	+6.453	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

MIR378E by CEBPB expression — UCEC

Explore this box plot interactively →