CEBPB

Across TCGA pan-cancer cohorts, CEBPB RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated CEBPB data layer compared with 1 for mutation status and 7 for mass-spec protein.

The strongest signal is observed in uveal melanoma (UVM), where higher CEBPB RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CEBPB expression acts as an unfavorable survival marker, although some lineages such as SKCM and MESO show a favorable association.

UVM, KIRC, and KIRP are the cancer types where CEBPB RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Median	All	0.396	0.794	<.001	148	view →
KIRC	DFS	Median	All	0.550	0.701	<.001	105	view →
KIRP	DFS	Quartile	All	0.824	0.980	<.001	77	view →
LUSC	OS	Tertile	All	0.698	0.826	<.001	46	view →
UCS	DFS	Median	II,III,IV	0.186	0.535	.004	46	view →
LGG	DFS	Median	All	0.310	0.485	<.001	42	view →
PAAD	OS	Quartile	All	0.261	0.817	<.001	40	view →
LUAD	DFS	Median	All	0.744	0.836	.001	37	view →
LAML	DFS	Quartile	All	0.229	0.499	.002	28	view →
SKCM	OS	Tertile	All	0.463	0.280	.002	28	view →
MESO	DFS	Tertile	All	0.700	0.247	.006	27	view →
UCEC	DFS	Tertile	All	0.585	0.760	.002	26	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

CEBPB–UVM (OS)

Open the UVM breakdown →