CEBPA

Across TCGA patient cohorts, CEBPA protein abundance is significantly associated with the RNA expression of many other genes, with 7,178 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CEBPA-associated genes across cancer lineages are NPC2, CD52, and IL16. Each is linked with CEBPA in more than 3 cancer types. Because this analysis shows association rather than direction, both CEBPA-to-partner and partner-to-CEBPA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CEBPA versus NPC2 in GBM, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEBPA→partner) and Y-score (partner→CEBPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NPC2 →	+1.024	+0.692	<.001	<.001	3	4
GBM	CD52 →	+1.366	+0.528	.004	.001	3	4
GBM	IL16 →	+0.793	+0.694	<.001	<.001	3	4
GBM	HLA-DPB1 →	+1.206	+0.502	.001	.003	3	4
GBM	TREM2 →	+1.227	+0.825	<.001	<.001	3	4
LSCC	CEBPA-DT →	+0.778	+0.429	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,178 associations by consensus.

CEBPA vs NPC2 — GBM

Explore this scatter interactively →