CEBPA

Across TCGA cell cohorts, CEBPA RNA expression is significantly associated with the go_rna of many other GO terms, with 5,546 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CEBPA-associated GO terms across cancer lineages are White fat cell proliferation, Fat cell proliferation, and Negative regulation of membrane potential. Each is linked with CEBPA in more than 17 cancer types. Because this analysis shows association rather than direction, both CEBPA-to-partner and partner-to-CEBPA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, White fat cell proliferation grouped by CEBPA-low versus CEBPA-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CEBPA→partner) and Y-score (partner→CEBPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	White fat cell proliferation →	+1.925	+3.973	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Fat cell proliferation →	-0.421	-1.867	<.001	.005	3	14
LIVER	Negative regulation of membrane potential →	-0.312	-3.575	<.001	.001	3	13
LIVER	Negative regulation of mitochondrial membrane potential →	-0.312	-3.575	<.001	.001	3	13
STOMACH	Morphogenesis of an epithelial fold →	+1.662	+2.812	<.001	<.001	3	10
LIVER	Cortisol metabolic process →	+1.427	+4.366	.006	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,546 associations by consensus.

White fat cell proliferation by CEBPA expression — LIVER

Explore this box plot interactively →