Across TCGA cell cohorts, CEACAM18 mutation is significantly associated with the RNA expression of many other genes, with 257 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEACAM18-associated genes across cancer lineages are KSR2, OR6V1, and OR2T11. Each is linked with CEACAM18 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEACAM18-to-partner and partner-to-CEACAM18 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM18→partner) and Y-score (partner→CEACAM18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KSR2 →	+0.315	+3.798	.003	.004	3	2
SKIN	OR6V1 →	+0.021	+2.560	<.001	.008	3	2
LUNG_SCLC	OR2T11 →	+0.020	+4.817	<.001	.001	3	1
BLOOD_Leukemia	AGXT2 →	+0.003	+4.569	<.001	.003	3	1
BLOOD_Leukemia	WFDC12 →	+0.163	+3.289	<.001	.009	3	1
BLOOD_Leukemia	DEFB4A →	+0.078	+3.684	.005	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 257 associations by consensus.

Exploration

CEACAM18 survival (RNA) · tumor vs normal (RNA) · all CEACAM18 data types